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417 - AIDS: in Africa, men are less responsive to treatment
November 2012
In Africa, more than 25 million people, most of them women, are currently infected by the AIDS virus. However, a study conducted by Epicentre( 1) and IRD researchers shows that men are less responsive to treatment. The provision of healthcare is intended to restore the level of lymphocyte cells, called T-CD4, reduced by HIV. Based on 13,000 patients monitored through four programmes carried out by Médecins sans frontières France in Malawi, Uganda and Kenya, the study shows that the reconstitution of these white blood cells is slower in men than in women.
Due to stigmatisation and work- and transport-related constraints, among others, men often receive healthcare at a later stage and are less responsive to treatment. However, this gender-based difference could also stem from biological causes, such as physiologically lower rates of T-CD4 lymphocytes.
This study underlines the fact that men should therefore receive special attention from programmes aimed at fighting the disease.
374 - Snakebites a public health problem in Africa
May 2011
One and a half million people per year are poisoned by snake venom in Sub-Saharan Africa. An IRD researcher recently analysed around 100 surveys and medical reports published over the past 40 years. No large-scale study of the situation had hitherto been conducted and public health authorities had underestimated the size of the problem. This means that currently only 10% of victims are treated, owing to a shortage of antivenoms * and lack of awareness among health care practitioners. Yet the clinical complications can be very serious, even fatal. A bite from a cobra or mamba can bring on death by asphyxia –due to respiratory paralysis– within 6h after the incident. Venom injected by the ocellated carpet viper, common in the African savannah, can cause haemorrhages leading to the victim’s death in a few days.
This new study provides authorities with more detailed and reliable figures which should enable them to readjust their health-care services in better tune with needs.
373 - Increasing rice production using genes from the African species
May 2011
Rice is the world’s most commonly used cereal food, feeding half of humanity. However, rice production will have to double within 20 years from now to meet the needs of a growing population.
Two species are used for cultivation, one Asian and the other African. The Asian species gives much stronger agronomic performances, but the African one is more rustic, more resistant to pathogens, more tolerant to drought and soil salinity.
With the aim of transferring these properties to Asian rice, IRD scientists and their research partners( 1) are seeking to overcome the sterility between the two species( 2). They used genome sequencing to compare the structure of a portion of chromosome, identified as the factor behind the reproductive barrier. These investigations, the first results of which were published recently in the journal PLoS One , have led to the definition of genetic markers allowing more rapid development of fertile lineages of improved Asian rice.
Darwin’s dream : the evolution of African cichlids
April 2009
The crisis in Kenya : one conflict among others
February 2008
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