Summary

Triwibowo Ambar Garjito, a researcher at the Institute for Disease Vector and Reservoir Research and Development (IVRCRD), National Institute of Health Research and Development (NIHRD), brilliantly defended his thesis on December 16, 2020 in Jakarta. Triwibowo was hosted at HSM and was enrolled in the CBS2 Doctoral School of the University of Montpellier

His thesis, entitled Dynamic of the main mosquito-borne diseases in Indonesia, was defensed in front of the jury composed as follows:

  • Indra Vythilingam, Professor at Malaya University, rapporteur
  • Christian Devaux, Research Director at CNRS, rapporteur 
  • Mustofa, Professor at Gadjah Mada University, examiner
  • Tri Baskoro Tunggul Satoto, Associate Professor at Gadjah Mada University, examiner
  • Ristiyanto, Research Director at IVRCRD, Examiner
  • Françoise Mathieu-Daudé, Research Fellow at IRD, examiner
  • Sylvie Manguin, Research Director at IRD, thesis director
  • Roger Frutos, Research Director at CIRAD, thesis director

Thesis abstract

This PhD work focuses on the study of the dynamics of the main mosquito-borne diseases in Indonesia, namely Japanese encephalitis, malaria, dengue and chikungunya. Several useful

results in public health were obtained during this PhD work. With respect to Japanese encephalitis, the presence of genotype I has been demonstrated in Indonesia. This is essential because this genotype is not detected by current tests and bypasses vaccination. With regard to malaria, the work has led to the identification of a new species of Anopheles, vector on the island of Java. The work on surveillance methods for arbovirus Aedes mosquito vectors provides important information for the control of diseases such as dengue or chikungunya. This PhD work has shown for the first time through a very large statistical study, that the Stegomyia indices, recommended by WHO, and used in Indonesia and other countries, are of no use in managing the risk of epidemics of dengue fever. This work has also shown a massive and rapid replacement of Aedes populations in Indonesia, which has a major impact on control strategies. There was also a replacement of the chikungunya virus lineages, which corresponds to a very invasive genotype that we propose to name Asia-Pacific. In conclusion, management and monitoring tools must be changed and new predictors must be developed.

Congratulations, Trwibowo!

Triwibowo Ambar Garjito durant sa soutenance virtuelle
Triwibowo Ambar Garjito during his virtual thesis defense